说起益生菌,人们总是能想到促进消化,维持肠道菌群结构平衡,提高集体免疫力等等。一些研究显示,部分益生菌的组合可产生协同增效的作用,对于调节情绪有积极作用,比如乳杆菌Rosell-52和长双歧杆菌Rosell-175。今天中宏生物(1)小编来和大家聊聊瑞士乳杆菌Rosell-52。
瑞士乳杆菌 Rosell-52是一种益生菌,也称为乳酸杆菌(或乳杆菌),2008 年之前, Rosell-52在分类学上被认为是嗜酸乳杆菌. 2008 后被重新分类,现在叫做瑞士乳杆菌。
ROSELL-52 部分相关研究
1.Rosell-52可能对一般的焦虑和抑郁迹象产生有益影响并减少日常生活压力[1]
2.Rosell-52可以对人们由于经受慢性压力产生的胃肠道症状(腹痛、恶心)产生有益的影响。它改善压力导致的心血管症状.[2]
3.与预防疗法相结合,Rosell-52 通过增加抗炎细胞因子(il - 10)的生产和抑制促炎细胞因子的生产(如 TNF-a, IL-8)减少不同大脑区域(边缘系统)中都发生的凋亡倾向(凋亡伴随心肌梗死)。它也可减少促炎细胞因子水平的升高,对抑郁产生影响..[3]
4.Rosell -52 联用 Rosell-11 经综述证明对肠道易激综合症(IBS), 抗生素相关性腹泻(AAD), H. pylori 消除和乳糖不耐受有益处.. [Foster, 2011]
5.Rosell-52对防止儿童感染有帮助[4]
6.Rosell-52减少IL-8 和 RANTES,在 LPS 刺激的细胞中增加免疫细胞增殖[5]
7.Rosell-52 发酵的牛奶通过加强 IgA-分泌细胞的数量等使产品赋予免疫增强功能和抗肿瘤特性[6,7]
8.Rosell-52 显著降低病原菌在上皮细胞的附着, 尤其是对 C. jejuni[8]
9.Rosell-52 加速急性肠道细菌感染的治疗过程 (如真菌感染, C. rodentium) [9]
10.Rosell-52 减少入侵病原体的水平及致病性.[10]
最后还要提醒大家一点,益生菌虽可减轻焦虑、抑郁症等精神心理疾病,但只能起到辅助治疗的作用,千万不要以此来代替常规药物治疗,以免导致病情复发或者加重。
中宏生物工程有限责任公司简称“中宏生物”,成立于1998年,是世界500强中粮集团成员企业。
参考文献:
Logan AC & Katzman M. Majordepressive disorder:probioticsmay be an adjuvanttherapy.2005 Med Hypotheses64, 533–538.
LaurentDiop, Sonia Guilloub,Henri Durand.Probioticfood supplementreduces stress-induced gastrointestinalsymptomsin volunteers: a double
blind,placebo-controlled,randomizedtrial. NutritionResearch 28 (2008) 1–5.
Stéphanie-AnneGirard,Thierno MadjouBah, Sévan Kaloustian,LauraLadaMoldovan,Isabelle Rondeau,ThomasA. Tompkins,Roger Godboutand GuyRousseau.Lactobacillushelveticusand Bifidobacteriumlongumtakenin combinationreduce the apoptosispropensityin the limbic system after myocardialinfarctionin a rat model. British Journalof Nutrition (2009), page 1 of 6.
CazzolaM, Pham-ThiN, Kerihuel JC, DurandH, BohbotS. Efficacyof a synbioticsupplementationin the preventionof common winter diseasesin children:a randomized,double-blind,placebo-controlledpilot study.Ther Adv Respir Dis. 2010 Oct;4(5):271-8. Epub 2010 Aug 20 J.F. Bisson,S. Hidlgo,M. Messaoudi.
TimothyD. Wallace,ShannonBradley,Nicole D. Buckley,and Julia M. Green Johnson.Interactionsof Lactic Acid Bacteria with Human Intestinal EpithelialCells: Effects on CytokineProduction.Journal of Food Protection.2003. Vol 66 No 3, p 466-472.
J. G. LeBlanc, C. Matar, J. C. Valdez,J. LeBlanc, and G. Perdigon.ImmunomodulatingEffects of PeptidicFractionsIssued from MilkFermented with Lactobacillushelveticus.J. Dairy Sci. 85:2733–2742.
AmandaFlander,ShannonBradley,Perry C. Johnson-Green,andJulia M. Green-Johnson.Effects of Lactic Acid Bacteria and Fermented Milkson EicosanoidProductionby IntestinalEpithelialCells. Journal of Food Science. Vol 70, Nr 2, 2005.
EytanWine, MélanieG. Gareau, Kathene Johnson-Henry& PhilipM. Sherman.Strain-specificprobiotic(Lactobacillushelveticus)inhibitionof Campylobacter jejuniinvasion of humanintestinalepithelialcells. Federationof EuropeanMicrobiologicalSocieties, 2009. 146-152.
M.Kostrzynska.Mechanismof colonizationand up-regulationof mucin gene expression by probiotics.2005.
Lepp, D. and Kostrzynska,M. Interactionsbetween lactobacilliandgastrointestinalpathogens,presented at the CanadianInstitute of Food Science TechnologyMeeting, Guelph (Ontario),May17-19. 2004.
免责声明:市场有风险,选择需谨慎!此文仅供参考,不作买卖依据。